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Effect of antibacterial effects of myrrh, rhatany, chamomomilla against to oral microorganisms

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¹éÇѽ ( Baek Han-Seung ) - °æÈñ´ëÇб³ Ä¡ÀÇÇÐÀü¹®´ëÇпø ¾È¸éÅëÁõ±¸°­³»°úÇб³½Ç
°­¼ö°æ ( Kang Soo-Kyung ) - °æÈñ´ëÇб³ Ä¡ÀÇÇÐÀü¹®´ëÇпø ¾È¸éÅëÁõ±¸°­³»°úÇб³½Ç
¾î±Ô½Ä ( Auh Q-Schick ) - °æÈñ´ëÇб³ Ä¡ÀÇÇÐÀü¹®´ëÇпø ¾È¸éÅëÁõ±¸°­³»°úÇб³½Ç
Àü¾çÇö ( Chun Yang-Hyun ) - °æÈñ´ëÇб³ Ä¡ÀÇÇÐÀü¹®´ëÇпø ¾È¸éÅëÁõ±¸°­³»°úÇб³½Ç
È«ÁøÇ¥ ( Hong Jung-Pyo ) - °æÈñ´ëÇб³ Ä¡ÀÇÇÐÀü¹®´ëÇпø ¾È¸éÅëÁõ±¸°­³»°úÇб³½Ç

Abstract

¿©·¯ ½Ä¹°ÀÇ ÃßÃâ¹°¿¡ ´ëÇÑ Ç×±ÕÈ¿°ú¿Í Ç×±ÕÀÛ¿ëÀº ÀÌ¹Ì ¿¬±¸µÇ¾î ÀÖÀ¸³ª, ±¸°­ ³» º´¿ø±Õ¿¡ ´ëÇÑ ¿¬±¸´Â ¾ÆÁ÷ ¹Ì¹ÌÇÑ ÆíÀÌ´Ù. ÀÌ¿¡ Ÿ¾×¿¡ ¼ö Á¾ÀÇ ½Ä¹° ÃßÃâ¹°, myrrh, rhatany, chamomomilla¸¦ ÷°¡ÇÏ¿© Ä¡ÁÖÁúȯ°ú ±¸Ãë ¹ß»ý¿¡ Áß¿äÇÑ ¿ªÇÒÀ» ÇÏ´Â ¿øÀαյ鿡 ´ëÇÑ ¾ïÁ¦È¿°ú¸¦ ÆľÇÇÏ°íÀÚ ÇÏ¿´´Ù.
½ÇÇè¿¡ »ç¿ëÇÑ »ý¾à ÃßÃâ¹°Àº Myrrh tincture (100 mg/ml), Ratanhia tincture (100 mg/ml), Chamomile tincture (100 mg/ml)¸¦ »ç¿ëÇÏ¿´À¸¸ç, ÃæÄ¡¿øÀαÕÀÎ S. mutans GS5, S. sobrinus 6715¿Í Ä¡ÁÖ¿°¿øÀαÕÁÖÀÎ P. gingivalis 2561 ¹× P. intermedia ATCC 25611, Candida albicans ATCC 18804, E. feacalis ATCC 4083 ±ÕÁÖ¸¦ ´ë»óÀ¸·Î Ç×±Õ½ÇÇèÇÏ¿© ´ÙÀ½°ú °°Àº °á°ú¸¦ ¾ò¾ú´Ù.
º» ¿¬±¸¿¡¼­ »ç¿ëÇÑ ½Ä¹° ÃßÃâ¹°ÀÎ myrrh, rhatany, chamomomilla´Â ¼ö·ÅÀÛ¿ë°ú »ì±ÕÀÛ¿ë, Ç׿°ÁõÀÛ¿ëÀ» °¡Áö°í ÀÖ´Â ¹°Áú·Î¼­, P. gingivalis, S. mutans, C. albicans µîÀÇ ±¸°­ ³» º´¿ø±Õ¿¡ ´ëÇÑ Ç×±ÕÈ¿°ú³ª Ç×±ÕÀÛ¿ëÀÌ ±¸¸íµÇ¾ú´Ù. ¶ÇÇÑ °¡Àå °­ÇÑ Ç×±ÕÈ¿°ú¸¦ º¸ÀÎ rhatany¸¦ ó¸®ÇÑ ÀÌµé º´¿ø±ÕÀ» Åõ°úÀüÀÚÇö¹Ì°æ ÇÏ¿¡¼­ °üÂûÇÏ¿´À» ¶§, ½ÉÇÑ ÇüÅÂÀû º¯ÇüÀÌ °üÂûµÇ¾ú´Ù. ÀÌ´Â ½Ä¹° ÃßÃâ¹°¿¡ ÀÇÇÏ¿© ±¸°­ ³» À¯ÇرÕÀ» ¾ïÁ¦½ÃÅ´À¸·Î½á Ä¡ÁÖÁúȯ°ú ÃæÄ¡, ±¸Ãë ¹× ±¸°­¿°ÀÇ ¹ß»ýÀ» ¿¹¹æÇÒ ¼ö ÀÖ´Ù´Â °ÍÀ» ÀǹÌÇϹǷÎ, ÇâÈÄ ±¸°­ ȯ°æ °³¼±À» À§ÇÑ ÀÓ»óÀû ±Ù°Å°¡ ¸¶·ÃµÉ ¼ö ÀÖÀ» °ÍÀ¸·Î »ý°¢µÈ´Ù.

Even though there exist a lot of study about antibacterial effects and reactions of extracted materials from plant, few study exist about oral pathogenic bacteria. Therefore we tried to recognize about the suppression effect to the periodontal pathogenic bacteria and halitosis, when add some kinds of plant extracted materials, myrrh, rhatany, chamomolilla to saliva.
We used Crude drug : Myrrh tincture (100mg/ml), Ratanhia tincture (100mg/ml), Chamomile tincture(100mg/ml). We inspected about the cariogenic bateriae, S. mutans GS5 and S. sobrinus 6715, periodontal pathogenic bacteria, P. gingivalis 2561, P. intermedia ATCC 25611, Candida albicans ATCC 18804, and E. feacalis ATCC 4083 , then the result follow.
The plant extracted material, myrrh, rhatany, chamomomilla, which have convergence effect, bacteriocidal effect and anti-inflammation effect, show an antibacterial effect and reaction to the oral pathogenic bacteria. And with treating rhatany that have the most strong antibacterial effect, through transmission electron microscopy we could see a severe morphologic change of bacteria. This means with the plant extracted material, we can suppress the oral harmful bacteria and prevent periodontal diseases, caries, halitosis and oral inflammations. And within the future studies for the improvement of oral hygiene, our result might be a clinical evidence.

Å°¿öµå

±¸°­ À¯ÇØ ¼¼±Õ; ¶óŸ´Ï¾Æ; ¸ô¾à; Ä«¸ð¹Ð·¹
chamomomilla; myrrh; oral harmful bacteria; rhatany

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